Publications

Targeted metabolic profiling of the Tg197 mouse model reveals itaconic acid as a marker of Rheumatoid...

Biomedcode coauthors a publication on the identification of a biomarker with translational value for the diagnosis & monitoring of rheumatoid...

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Characterization and non-clinical assessment of the proposed etanercept biosimilar GP2015 with originator...

Biomedcode's human TNF transgenic arthritis model, (Tg197), contributes to the non-clinical assessment of etanercept biosimilar GP2015 with...

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Regulation of tumour necrosis factor signalling: live or let die

Brenner D, Blaser H, Mak TW, 2015, Nat. Rev. Immunol., May 26;15(6):362-74. doi: 10.1038/nri3834. Abstract: Tumour necrosis factor (TNF) is a...

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Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess...

UCB Celltech & Biomedcode co-author a new paper demonstrating that CAIA in the human TNF transgenic (Tg1278TNFko) mice is a well-suited animal...

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FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

FHL2 serves as a protective factor and that, rather than promoting the pathology, the upregulation of FHL2 in RA occurs in frame of a regenerative...

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NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB

Zhang H, Hilton MJ, Anolik JH, Welle SL, Zhao C, Yao Z, Li X, Wang Z, Boyce BF and Xing L, 2014, J Clin Invest. 2014;124(7):3200-3214....

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Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo...

Biomedcode's Tg197 transgenic model of rheumatoid arthritis were used to the test efficacy of various anti-TNF antibodies.

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via...

The paper is using miR-seq-based profiling in SF from the TghuTNF mouse model and validations in RA patient biopsies to identify miR-221/222 and...

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A non-innovator version of etanercept for treatment of arthritis.

Maity S, Ullanat R, Lahiri S, Shekar S, Sodhan G, Vyas A, Dyaga G, Ireni S, Nair N, Sotsios Y, Maria DC, Morawala-Patell V., Biologicals, 2011...

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Anti-TNFα domain antibody construct CEP-37247: Full antibody functionality at half the size.

A publication on a novel antibody characterization where the experiments were performed using Tg197 transgenic mouse model by Biomedcode.

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