Publications

Targeted metabolic profiling of the Tg197 mouse model reveals itaconic acid as a marker of Rheumatoid...

Biomedcode coauthors a publication on the identification of a biomarker with translational value for the diagnosis & monitoring of rheumatoid...

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Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of...

Biomedcode's mouse models offered the in vivo non-clinical proof validating the efficacy of a novel composite hydrogel tacrolimus formulation for...

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Frailty in mouse ageing: A conceptual approach

von Zglinicki T, Nieto IV, Brites D, Karagianni N, Ortolano S, Georgopoulos S, Cardoso AL, Novella S, Lepperdinger G, Trendelenburg AU, et al. Mech...

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Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess...

UCB Celltech & Biomedcode co-author a new paper demonstrating that CAIA in the human TNF transgenic (Tg1278TNFko) mice is a well-suited animal...

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Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis

Highlight the dominant role of subepithelial myofibroblasts in sensing inflammation and tissue damage and promoting intestinal homeostasis through...

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FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

FHL2 serves as a protective factor and that, rather than promoting the pathology, the upregulation of FHL2 in RA occurs in frame of a regenerative...

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Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like...

A study of the psoriasis pathogenesis unraveling new keratinocyte-intrinsic mechanisms linking TNFR1, NF-κB, ERK, IL-24, IL-22R1, and STAT3...

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Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

A remarkable therapeutic application based on the differential sensitivity that epithelial and endothelial tissues exhibit to TNF-induced lethal...

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Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo...

Biomedcode's Tg197 transgenic model of rheumatoid arthritis were used to the test efficacy of various anti-TNF antibodies.

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via...

The paper is using miR-seq-based profiling in SF from the TghuTNF mouse model and validations in RA patient biopsies to identify miR-221/222 and...

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