Publications

Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis

Highlight the dominant role of subepithelial myofibroblasts in sensing inflammation and tissue damage and promoting intestinal homeostasis through...

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FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

FHL2 serves as a protective factor and that, rather than promoting the pathology, the upregulation of FHL2 in RA occurs in frame of a regenerative...

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NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB

Zhang H, Hilton MJ, Anolik JH, Welle SL, Zhao C, Yao Z, Li X, Wang Z, Boyce BF and Xing L, 2014, J Clin Invest. 2014;124(7):3200-3214....

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Novel Genetic Models of Osteoporosis by Overexpression of Human RANKL in Transgenic Mice

RinotasV, Niti A, Dacquin R, Bonnet N, Stolina M, Han CY, Kostenuik P, Jurdic P, Ferrari S and Douni E., J Bone Miner Res., 2014 May;29(5):1158-69....

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Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like...

A study of the psoriasis pathogenesis unraveling new keratinocyte-intrinsic mechanisms linking TNFR1, NF-κB, ERK, IL-24, IL-22R1, and STAT3...

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Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

A remarkable therapeutic application based on the differential sensitivity that epithelial and endothelial tissues exhibit to TNF-induced lethal...

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Are spondylarthritides related but distinct conditions or a single disease with a heterogeneous phenotype?

The article proposes that a disease or condition is primarily defined by its pathophysiology rather than by its phenotypic presentation

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Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo...

Biomedcode's Tg197 transgenic model of rheumatoid arthritis were used to the test efficacy of various anti-TNF antibodies.

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via...

The paper is using miR-seq-based profiling in SF from the TghuTNF mouse model and validations in RA patient biopsies to identify miR-221/222 and...

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A non-innovator version of etanercept for treatment of arthritis.

Maity S, Ullanat R, Lahiri S, Shekar S, Sodhan G, Vyas A, Dyaga G, Ireni S, Nair N, Sotsios Y, Maria DC, Morawala-Patell V., Biologicals, 2011...

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