Always aiming at high quality services coupled to true customer focus, Biomedcode has built its reputation steadily over the years gaining the trust and respect of its clients.
| Figure: Percentage of contracts closed per country for
years 2006 to 2015 (click on image to enlarge it).
Since its establishment, Biomedcode has attracted clients from Europe, the United States, Asia and Australia some of them ranked among the top 5 pharmaceutical companies worldwide.
Preclinical data generated following our successful collaboration with our clients, have been incorporated in IND applications for FDA, SFDA & EMEA approval.
1. Moore A, Allden S, Bourne T, Denis MC, Kranidioti K, Okoye R, Sotsios Y, Stencel Z, Vugler A, Watt G, et al. 2014. Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis. J Transl Med. 2014 Oct 25;12(1):285. [Epub ahead of print] PubMed PMID: 25344414. (view article)
UCB Celltech & Biomedcode co-author a new paper demonstrating that CAIA in the human TNF transgenic (Tg1278TNFko) mice is a well-suited animal model for testing the next generation of therapeutics that will target human TNFα in rheumatoid arthritis.
2. Kanakaraj P, Puffer BA, Yao XT, Kankanala S, Boyd E, Shah RR, Wang G, Patel D, Krishnamurthy R, Kaithamana S, Smith RG, LaFleur DW, Barbas CF 3rd, Hilbert DM, Kiener PA, Roschke VV, 2012. Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis. MAbs. 2012 Sep-Oct;4(5):600-13. doi: 10.4161/mabs.21227. Epub 2012 Aug 6. PMID:22864384.
Biomedcode's Tg197 transgenic model of rheumatoid arthritis were used to the test efficacy of various anti-TNF antibodies. (view article)
3. Maity S, Ullanat R, Lahiri S, Shekar S, Sodhan G, Vyas A, Dyaga G, Ireni S, Nair N, Sotsios Y, Denis MC, Morawala-Patell V, 2011 . A non-innovator version of etanercept for treatment of arthritis. Biologicals. 2011 Nov;39(6):384-95. doi: 10.1016/j.biologicals.2011.08.014. Epub 2011 Oct 12. PubMed PMID: 21996051. (view article)
4. Gay RD, Clarke AW, Elgundi Z, Domagala T, Simpson RJ, Le NB, Doyle AG, Jennings PA, 2010. Anti-TNFα domain antibody construct CEP-37247: Full antibody functionality at half the size. MAbs, 2010 Nov-Dec;2(6):625-38. (view article)
A publication on a novel antibody characterization where the experiments were performed using Tg197 transgenic mouse model by Biomedcode.