Preclinical Platfrorms

Biomedcode offers preclinical testing of human therapeutics using standardized and validated preclinical platforms based on humanized and wild type mouse models of chronic and acute inflammatory diseases closely recapitulating human pathologies.

Disease Indications

  • Arthritis
  • Spondyloarthritis
  • Psoriasis
  • Osteoporosis
  • IBD
  • Multiple Sclerosis
  • Acute inflammation

Routes of Administration

  • Intraperitoneal
  • Subcutaneous
  • Intradermal
  • Per Os
  • Intravenous
  • Intraarticular
  • Implantation

Analysis options

  • In vivo scoring
  • Histopathology
  • uCT imaging
  • PK/PD sampling
  • Tissue collection
  • ELISA analysis
  • FACS analysis
  • Pharmacogenomis

Our success stories

  • Moore AR et al (2014). Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid 
arthritis. J Transl Med, 12(1):285 (view article).
  • Hofmann HP et al. (2016). Characterization and non-clinical assessment of the proposed etanercept biosimilar GP2015 with originator etanercept (Enbrel®).  Expert Opinion on Biological Therapy, 16(10)10 (view article).
  • Gabriel D et al. (2016). Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis. J Control Release. S0168-3659(16)30702-7  (view article).