Biomedcode’s preclinical models: Priming drugs for success but also … predicting drug failure!A new clinical study published by GlaxoSmithKline confirms findings in Biomedcode's TNF-DARE models.
30 SEP 2015
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Therapeutic Areas - Animal models
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Biomedcode is modeling human inflammatory conditions:
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Biomedcode was founded in 2006, as a spin-off of the Biomedical Sciences Research Center “Alexander Fleming”
Biomedcode has extensive expertise & scientific excellence in inflammatory & autoimmune animal disease models
Our mouse models of arthritis were instrumental in proving the efficacy of anti-hTNF therapeutics in arthritis
Biomedcode’s clients include top 5 worldwide pharmaceutical companies
Animal models as a tool to dissect pivotal pathways driving spondyloarthritisVieira-Sousa E, van Duivenvoorde LM, Fonseca JE, Lories RJ, Baeten DL. Arthritis Rheumatol. 2015 Jul 20. doi: 10.1002/art.39282. [Epub ahead of...
Regulation of tumour necrosis factor signalling: live or let dieBrenner D, Blaser H, Mak TW, 2015, Nat. Rev. Immunol., May 26;15(6):362-74. doi: 10.1038/nri3834. Abstract: Tumour necrosis factor (TNF) is a...
Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments...UCB Celltech & Biomedcode co-author a new paper demonstrating that CAIA in the human TNF transgenic (Tg1278TNFko) mice is a well-suited animal...