Tg3647 mice over-express human TNF that leads to the gradual development of spontaneous slow progressing chronic inflammatory polyarthritis with 100% penetrance.

Histopathological progression of arthritis pathology with age in the Tg3647 model of arthritis


 Download the whitepaper to learn more on:

  • The disease model
  • Study design
  • Routes of administration
  • Validation data
  • Readouts
  • Analysis options